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The most characteristic histological finding ivas an interlobular bile duct damage which correlated with the presence of tymphoid aggregates in the portal tracts and with the development of fibrosis. The prevalence and the clinico -pathologic findings of PET positive parotid lesions have not been known. We investigated how often incidental parotid lesions are found on clinical FDG-PET studies and what the clinico -pathologic characteristics of those parotid lesions are in the present study. Final diagnosis was made by pathologic analysis or clinical follow-up assessment.
Fifteen 0. The maxSUV ranged from 1. All of incidentally found parotid lesions in clinical FDG-PET studies were confirmed as benign lesions with prevalence of 0. Close follow up using PET or CT might be a reasonable approach for determining the nature of incidentally found parotid lesions. Dos estudios de casos. Maspin mammary serine protease inhibitor is a member of the serpin super family of protease inhibitors and is known to have tumor-suppressor function in breast and prostate cancers, acting at the level of tumor invasion and metastasis. However, there have been no published data regarding the role of Maspin in squamous cell carcinoma SCC and transitional cell carcinoma TCC of urinary bladder.
Patients and Methods: We have evaluated the immunohistochemical expression of Maspin and p53 in a series of bladder cancer patients 56 SCC and 78 TCC and the interrelationship between Clinico pathological features and Maspin and p53 expression. Results: There was positive Maspin expression in High Maspin expression was found in low grade p Clinico pathological parameters including gender, clinical stage and Bilharzial infestation.
These results indicated that Maspin expression might predict a better prognosis for bladder carcinoma. Also Maspin probably could play a role in tumor progression. We found no significant association between both Maspin and p53 expression and bilharziasis in TCC and SCC; this indicated that Maspin and p53 expression could be prognostic factors in both bilharzial and non. Differential DNA methylation profiles in gynecological cancers and correlation with clinico -pathological data.
Full Text Available Abstract Background Epigenetic gene silencing is one of the major causes of carcinogenesis.
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